E. Aubrey Thompson

This study compares immune cell deconvolution and cancer subtype gene signatures in TNBC, finding that immune aggregates better predict outcomes than subtype signatures.

The paper uses single-cell multiomics to identify shared and unique immune dysfunction features in Parkinson's disease and inflammatory bowel disease across gut, plasma, and stool samples.

This study shows that specific MHC class I molecules on brain endothelium regulate CD8 T cell activity and neuropathology in experimental cerebral malaria.

This study evaluates RNA extraction and capture methods for RNA-seq from FFPE tissues, finding high correlation in gene expression profiles with sufficient RNA quality and demonstrating improved fusion detection with TruSeq RNA Access.