Author

Cori E. Fain

Mayo ClinicORCID 0000-0002-8323-6419Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:flow cytometry· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Katayoun AyasoufiiD· 3 shared Aaron J. JohnsoniD· 2 shared Jie SuniD· 2 shared Abudumijiti Aibaidula· 1 shared AJ Johnson· 1 shared Alexandra M. Hoyt-MiggelbrinkiD· 1 shared AR Dropik· 1 shared Bibo ZhuiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

Katayoun AyasoufiORCID

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3 papers

Recent·Most cited

Antigen-specific CD8 T cells are generated and reactivated in the bone marrow following viral brain infections and impact the bone marrow niche

Delaney M. Wolf, Kelly M. Hotchkiss, Rachael Ann Reesman, Christian Karl Pfaller, Eliese Moelker, Alexandra M. Hoyt-Miggelbrink, Cori E. Fain, Kathryn E. Blethen, Pamela K. Norberg, Shannon E. Wallace, Vatsal Jain, Gerald Arthur Grant, Mustafa Khasraw, Vidyalakshmi Chandramohan, Aaron J. Johnson, Katayoun Ayasoufi

This study shows that virus-specific CD8 T cells are generated and reactivated in the bone marrow after brain viral infections, leading to changes in the bone marrow niche.

bioRxiv · Dec 26, 2025 · PreprintImmunology

Temporal single-cell profiling uncovers age-associated delays in immune resolution to respiratory viral infection

Yue Wu, Chaofan Li, Jinyi Tang, Xiaochen Gao, In Su Cheon, Bibo Zhu, Ruixuan Zhang, Cori E. Fain, Shengen Shawn Hu, Harish Narasimhan, Gislane de Almeida Santos, Katayoun Ayasoufi, Aaron J. Johnson, Hui Zong, Chongzhi Zang, , Jie Sun

This study identifies age-associated delays in immune resolution to respiratory viral infection by analyzing single-cell RNA sequencing and flow cytometry data from young and aged mice.

bioRxiv · Dec 17, 2025 · PreprintImmunology

Antigen presentation by discrete class I molecules on brain endothelium dynamically regulates T-cell mediated neuropathology in experimental cerebral malaria

Cori E. Fain, Jiaying Zheng, F Jin, Katayoun Ayasoufi, Y Wu, MT Lilley, AR Dropik, DM Wolf, RC Rodriguez, Abudumijiti Aibaidula, Zachariah Peter Tritz, Samantha M. Bouchal, LL Pewe, Stina Lisa Urban, Y Chen, , AJ Johnson

This study shows that specific MHC class I molecules on brain endothelium regulate CD8 T cell activity and neuropathology in experimental cerebral malaria.

bioRxiv · Oct 30, 2022 · PreprintNeuroscience