Author

Natalie Ertl

Hammersmith HospitalORCID 0000-0002-9010-1870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 8 Assay:imaging· 8 Approach:statistical model· 8 Research Focus:cell-cell communication· 6 Research Focus:benchmarking· 1

Frequent Co-Authors

Matthew B. WalliD· 7 shared David John NuttiD· 5 shared H. Valerie CurraniD· 4 shared Will LawniD· 4 shared Claire MokrysziD· 3 shared David ErritzøeiD· 3 shared Kat PetrilliiD· 3 shared Shelan Ofori· 3 shared

Activity by Year

2020-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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7 shared papersNeuroscience

Matthew B. WallORCID

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Author profile →

8 papers

Recent·Most cited

Longitudinal fMRI reveals altered developmental trajectories of functional network organisation associated with adolescent cannabis use

Elizabeth J Davies, Natalie Ertl, Freeman Tom P., Anya Borissova, Rachel Lees Thorne, Shelan Ofori, Kat Petrilli, Clare Mokrysz, H. Valerie Curran, Will Lawn, Matthew B. Wall

This study uses longitudinal fMRI to show that adolescent cannabis use is associated with distinct changes in functional network organisation compared to adults.

bioRxiv · Oct 24, 2026 · PreprintNeuroscience

Neurite Complexity and Plasticity Markers Track Synaptic Vesicle Density in the Living Human Brain: A Multimodal PET-MRI-EEG Study

Claudio Agnorelli, Joseph M. Peill, Danielle L. Kurtin, Orla Mallon, Gabriela Sawicka, Ekaterina Shatalina, Kate E.M. Godfrey, Robin J. Murphy, Kirran Ahmad, Lena Oestreich, Rachael L. Sumner, Manfredi Alberti, Matthew Wall, Natalie Ertl, Graham E. Searle, , David Erritzøe

This study links synaptic vesicle density measured by PET with structural and functional neuroplasticity markers using multimodal imaging and EEG in healthy volunteers.

bioRxiv · Oct 13, 2026 · PreprintNeuroscience

Structural and functional MRI signatures of Gambling Disorder: a case-control study

Rayyan R. Zafar, Natalie Ertl, Luke Donegan, Oliver Downes, Shayam Suseelan, Maxim Siegel, Elinor Farrell, Alan Cross, Philip Adkins, Venetia Leonidaki, Danielle L. Kurtin, Louise M. Paterson, Matthew B. Wall, Henrietta Bowden‐Jones, David Nutt, David Erritzøe

This study identifies structural and functional MRI differences in Gambling Disorder compared to healthy controls, highlighting brain regions and connectivity patterns associated with the disorder.

bioRxiv · Sep 15, 2026 · PreprintNeuroscience

Dissociable effects of LSD and MDMA on striato-cortical connectivity in healthy subjects

Natalie Ertl, Imran Ashraf, Lisa Azizi, Leor Roseman, David Erritzøe, David Nutt, Robin Lester Carhart-Harris, Matthew B. Wall

This study examines how LSD and MDMA affect striato-cortical connectivity in healthy subjects using resting-state fMRI, finding distinct changes in connectivity patterns between the striatum and other brain regions.

Neuropsychopharmacology · Oct 31, 2025Peer-reviewedNeuroscience

Receptor-enriched analysis of functional connectivity (REACT) for understanding cannabinoid neuropsychopharmacology

Ekaterina Shatalina, Natalie Ertl, Kat Petrilli, Shelan Ofori, Anna Borissova, Claire Mokrysz, H. Valerie Curran, Will Lawn, Tom P. Freeman, Oliver David Howes, Matthew B. Wall

This study investigates how THC and CBD affect CB1 and CB2 receptor-enriched functional connectivity using REACT analysis in cannabis users.

bioRxiv · Jun 2, 2025 · PreprintNeuroscience

Associations between regular cannabis use and brain resting-state functional connectivity in adolescents and adults

Natalie Ertl, Will Lawn, Claire Mokrysz, Tom P. Freeman, Naji Alnagger, Anna Borissova, Natalia Fernandez‐Vinson, Rachel Lees, Shelan Ofori, Kat Petrilli, Katie Trinci, Essi M. Viding, H. Valerie Curran, Matthew B. Wall

This study examines the effects of regular cannabis use on brain resting-state functional connectivity in adolescents and adults, finding localized increases in the executive control network in users but no significant age-group interactions.

Journal of Psychopharmacology · Jul 29, 2023Peer-reviewedNeuroscience

Increased low-frequency brain responses to music after psilocybin therapy for depression

Matthew B. Wall, Cynthia Lam, Natalie Ertl, Mendel Kaelen, Leor Roseman, David John Nutt, Robin Lester Carhart-Harris

This study shows that psilocybin therapy increases low-frequency brain responses to music in patients with treatment-resistant depression, correlating with subjective drug effects.

Journal of Affective Disorders · Apr 22, 2023Peer-reviewedNeuroscience

Individual and combined effects of Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) on striato-cortical connectivity in the human brain

Matthew B. Wall, Tom P. Freeman, Chandni Hindocha, Lysia Demetriou, Natalie Ertl, Abigail M. Freeman, A. Jones, Will Lawn, Rebecca Anne Pope, Claire Mokrysz, Daniel Solomons, Ben K. Statton, Hannah R Walker, Yumeya Yamamori, Zixu Yang, , Michael Bloomfield

This study examines how CBD and THC affect striato-cortical connectivity in the human brain using fMRI, finding THC disrupts connectivity while CBD mitigates some effects and has mixed impacts when used alone.

bioRxiv · Nov 20, 2020 · PreprintNeuroscience