Author

B.K. Pokharel

Fraunhofer Institute for Translational Medicine and PharmacologyORCID 0000-0002-9016-0520Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:benchmark study· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:large language model· 1 Organism:non-human primate· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Alisa Nicole DeGraveiD· 1 shared Brinton A. Seashore-LudlowiD· 1 shared Dinh-Long HuynhiD· 1 shared Elin AspiD· 1 shared Flavio BallanteiD· 1 shared Jonne RietdijkiD· 1 shared Jordi Carreras PuigvertiD· 1 shared Kristen Michelle NaderiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Alisa Nicole DeGraveORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Human-supervised Agentic AI for Hypothesis Generation and Experimental Assistance in Drug Repurposing

Dinh-Long Huynh, Elin Asp, Flavio Ballante, Jordi Carreras Puigvert, Alisa Nicole DeGrave, Reagon Karki, Kristen Michelle Nader, Päivi Östling, B.K. Pokharel, Jonne Rietdijk, Lars Schlotawa, Lina Schmidt, Srijit Seal, Brinton A. Seashore-Ludlow, Tero A. Aittokallio, Ola Spjuth

A human-supervised multi-agent LLM system covered drug repurposing from knowledge graph building to assay analysis in three case studies; retrospective COVID-19 screen AUC-ROC 0.986 without predefined thresholds.

bioRxiv · Aug 17, 2026 · PreprintBioinformatics✦ In-depth digest