Author

Lina Schmidt

RWTH Aachen University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Carolin Victoria SchneideriD· 2 shared Hélène F.E. GleitziD· 2 shared Rafael KramanniD· 2 shared Rebekka K. SchneideriD· 2 shared Adam BenabidiD· 1 shared Aleksandar V. Kargaliev· 1 shared Alexandru FloreaiD· 1 shared Alisa Nicole DeGraveiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Carolin Victoria SchneiderORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human-supervised Agentic AI for Hypothesis Generation and Experimental Assistance in Drug Repurposing

Dinh-Long Huynh, Elin Asp, Flavio Ballante, Jordi Carreras Puigvert, Alisa Nicole DeGrave, Reagon Karki, Kristen Michelle Nader, Päivi Östling, B.K. Pokharel, Jonne Rietdijk, Lars Schlotawa, Lina Schmidt, Srijit Seal, Brinton A. Seashore-Ludlow, Tero A. Aittokallio, Ola Spjuth

A human-supervised multi-agent LLM system covered drug repurposing from knowledge graph building to assay analysis in three case studies; retrospective COVID-19 screen AUC-ROC 0.986 without predefined thresholds.

bioRxiv · Aug 17, 2026 · PreprintBioinformatics✦ In-depth digest

Oncodevelopmental plasticity of the skeleton in myeloid neoplasms

Salim Atakhanov, Ian Ghezzi, Hector Tejeda Mora, Lucas Greven, Marta Rizk, Lina Schmidt, Katrin Goetz, Lina Merg, Valeria Solozobova, Adam Benabid, Pia Wanner, Niklas Lutterbach, Aleksandar V. Kargaliev, Mathias Schäfersküpper, Alexandru Florea, , Rebekka K. Schneider

This study identifies a novel mechanism in myelofibrosis where a single mutation drives both bone formation and resorption, revealing THBS1 as a therapeutic target.

bioRxiv · Mar 21, 2026 · PreprintCancer Biology

NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms

Hélène F.E. Gleitz, Mayra L. Ruiz Tejada Segura, James Shiniti Nagai, Stijn N. R. Fuchs, Gerjanne Vroeg in de Wei, Inge Snoeren, Giulia Cesaro, I. A. J. M. Bakker, Marta Gargallo Garasa, Jessica Ellen Pritchard, Tesa Klenovšek, Stephani Schmitz, Lina Schmidt, Eric Bindels, Twan Lammers, , Rebekka K. Schneider

This study identifies Spp1⁺ macrophages as key hubs coordinating fibrotic remodeling in myeloproliferative neoplasms using NicheSphere, a novel computational method for cell communication analysis.

bioRxiv · Mar 18, 2026 · PreprintCancer Biology