Author

Spencer E. Escobedo

Purdue University West LafayetteORCID 0000-0002-9026-9104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Alyssa EastoniD· 1 shared Hana HalliD· 1 shared Juan P P Jauregui-LozanoiD· 1 shared Nadia A. LanmaniD· 1 shared Vikki Marie WeakeiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMolecular Biology

Alyssa EastonORCID

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1 paper

Recent·Most cited

Proper control of R-loop homeostasis is required for maintenance of gene expression and neuronal function during aging

Juan P P Jauregui-Lozano, Spencer E. Escobedo, Alyssa Easton, Nadia A. Lanman, Vikki Marie Weake, Hana Hall

This study shows that R-loop accumulation in aging Drosophila photoreceptor neurons correlates with gene expression loss and visual function decline, and that Top3β and RNase H1 can mitigate these effects.

Aging Cell · Jan 20, 2022Peer-reviewedMolecular Biology