GeneticsbioRxivPreprint
Polycomb repression works without Siesta
Tatyana G. Kahn, Andres Garrido, A. A. Yushkova…·Yuri B. Schwartz
The paper shows that variant RING1 complexes in Drosophila can ubiquitylate H2A without being part of the Polycomb repression system, and that H2A ubiquitylation has minimal impact on transcriptional repression.
DOI 10.1101/2025.07.18.664654