Jonathan F. Lovell

Mice immunized with N1 neuraminidase in a single cycle infectious virus or in a recombinant nanoparticle vaccine are protected against lethal challenge with highly pathogenic avian influenza H5N1 influenza

This study shows that mice vaccinated with a single-cycle influenza virus or a neuraminidase-decorated nanoparticle are protected from lethal H5N1 influenza challenge.

Mesoscopic Fluorescence Imaging of Light-Triggered Chemotherapeutic Release in Cancer Spheroid Models

The paper evaluates a laparoscopic fluorescence imaging platform to quantify light-triggered drug release in cancer models, showing strong correlation with standard measurements and potential for guided treatment.

Multivalent administration of dengue E dimers on liposomes elicits type-specific neutralizing responses without immune interference

This study develops a tetravalent dengue vaccine using stabilized E dimers on liposomes, eliciting type-specific neutralizing antibodies without immune interference.

Quantitative Fluorescence Imaging of Porphyrin Phospholipid Photobleaching and Light Activated Liposomal Doxorubicin Release Using Wide-field and Laparoscopic SFDI in an Ovarian Cancer Model

This paper develops a laparoscopic SFDI system to monitor porphyrin phospholipid photobleaching and doxorubicin release in an ovarian cancer model, demonstrating its potential for real-time intraoperative monitoring of chemophototherapy.

Fluence rate-dependent kinetics of light-triggered liposomal doxorubicin assessed by quantitative fluorescence-based endoscopic probe

This paper develops an endoscopic probe to monitor light-triggered drug release from liposomal doxorubicin and validates its effectiveness in controlled settings.