Aravinda M. de Silva

This study develops a tetravalent dengue vaccine using stabilized E dimers on liposomes, eliciting type-specific neutralizing antibodies without immune interference.

This study evaluates a stabilized DENV2 E homodimer vaccine, finding it elicits broader neutralizing antibody responses targeting multiple E protein domains compared to the wild-type monomer.

This study shows that CD4+ T cell depletion before DENV infection affects antibody specificity and cross-reactivity during subsequent ZIKV infection in rhesus macaques.