Author

Devina Thiono

University of North Carolina at Chapel HillORCID 0000-0002-8330-0396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

Aravinda M. de SilvaiD· 2 shared Brian A. KuhlmaniD· 2 shared Ruby P. Shah· 2 shared Shaomin TianiD· 2 shared Thanh T.N. PhaniD· 2 shared Deanna ZhuiD· 1 shared Demetrios Samaras· 1 shared Gisselle Prida Ajo· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

Aravinda M. de SilvaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Multivalent administration of dengue E dimers on liposomes elicits type-specific neutralizing responses without immune interference

Thanh T.N. Phan, Devina Thiono, Matthew G. Hvasta, Ruby P. Shah, Gisselle Prida Ajo, Wei‐Chiao Huang, Jonathan F. Lovell, Shaomin Tian, Aravinda M. de Silva, Brian A. Kuhlman

This study develops a tetravalent dengue vaccine using stabilized E dimers on liposomes, eliciting type-specific neutralizing antibodies without immune interference.

npj Vaccines · Jun 9, 2025Peer-reviewedMicrobiology

Stabilized dengue virus 2 envelope subunit vaccine redirects the neutralizing antibody response to all E-domains

Devina Thiono, Demetrios Samaras, Thanh T.N. Phan, Deanna Zhu, Ruby P. Shah, Izabella N. Castillo, Lawrence J. Forsberg, Lakshmanane Premkumar, Ralph Steven Baric, Shaomin Tian, Brian A. Kuhlman, Aravinda M. de Silva

This study evaluates a stabilized DENV2 E homodimer vaccine, finding it elicits broader neutralizing antibody responses targeting multiple E protein domains compared to the wild-type monomer.

Journal of Virology · Apr 16, 2025Peer-reviewedMicrobiology