Author

Haolong Zhu

Johns Hopkins UniversityORCID 0000-0002-9056-0268Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Kevin AumilleriD· 2 shared William Basil LudingtoniD· 2 shared Allan C. SpradlingiD· 1 shared Ann Deng· 1 shared Benjamin ObadiaiD· 1 shared Jane L. Yang· 1 shared John M. UrbaniD· 1 shared Karina Gutiérrez-GarcíaiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

Kevin AumillerORCID

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3 papers

Recent·Most cited

MicrobiologyApplied and Environmental MicrobiologyPeer-reviewedAug 13, 2025

Commensal acidification of specific gut regions produces a protective priority effect against enteropathogenic bacterial infection

Jane L. Yang, Haolong Zhu, Puru Sadh…·William Basil Ludington

This study shows that a wild-derived Lactiplantibacillus plantarum strain protects Drosophila from Serratia marcescens infection by acidifying specific gut regions, creating a priority effect.

6 citations

Drosophilaimaging

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MicrobiologySciencePeer-reviewedDec 5, 2024

A conserved genetic basis for commensal-host specificity through live imaging of colonization dynamics

Karina Gutiérrez-García, Kevin Aumiller, Ren Dodge…·William Basil Ludington

The paper uses live imaging of Drosophila gut colonization to show that Lactiplantibacillus plantarum recognizes a specific niche via a conserved colonization island.

28 citationstop 1%

Drosophilaimaging

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Developmental BiologyeLifePeer-reviewedOct 13, 2023

Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cells

Liang-Yu Pang, Steven Z. DeLuca, Haolong Zhu…·Allan C. Spradling

The paper examines chromatin and gene expression changes in Drosophila female germline stem cells, revealing mechanisms of self-renewal and differentiation that resemble totipotent zygote development.

6 citations

DrosophilaChIP-seq

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