William Basil Ludington

This study examines how the timing of bacterial colonization during Drosophila development affects transcriptional responses and phenotypic outcomes, finding minor but distinct gene expression changes and persistent effects on specific genes.

This study shows that a wild-derived Lactiplantibacillus plantarum strain protects Drosophila from Serratia marcescens infection by acidifying specific gut regions, creating a priority effect.

PeakClimber accurately quantifies complex HPLC chromatograms using exponential Gaussian functions, outperforming existing tools in precision and applicability to biological samples.

This study identifies lactic acid from gut microbes as a key factor improving Drosophila survival during starvation by enhancing oxidative phosphorylation.

The paper uses live imaging of Drosophila gut colonization to show that Lactiplantibacillus plantarum recognizes a specific niche via a conserved colonization island.

The paper identifies master regulators in genetic and microbiome fitness landscapes by analyzing high-dimensional interactions beyond pairwise epistasis.

Bellymount allows long-term, non-invasive imaging of Drosophila abdominal organs and gut microbiota, enabling tracking of cellular and microbial dynamics over multiple days.

This study investigates how bacterial interactions in the Drosophila gut microbiome influence host fitness traits like development, reproduction, and lifespan.