Cell BiologyACS Chemical BiologyPeer-reviewed
Chemically Induced Nuclear Pore Complex Protein Degradation via E3 Ligase TRIM21
Xiaomei Li, Qingyang Wang, Anping Guo…·Dengfeng Dou
This study identifies small-molecule ligands for TRIM21, an E3 ligase, demonstrating their ability to degrade nuclear pore complex proteins and induce cell death in cancer cells.
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