Author

Madeleine Arseneault

McGill UniversityORCID 0000-0002-9101-8462Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Hamed Shateri NajafabadiiD· 2 shared Simon TanguayiD· 2 shared Yasser RiazalhosseiniiD· 2 shared Adrien OsakweiD· 1 shared Aldo Hernández-CorchadoiD· 1 shared Anie MonastiD· 1 shared Ariel MadrigaliD· 1 shared Ashot Harutyunyan· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Hamed Shateri NajafabadiORCID

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2 papers

Recent·Most cited

Single-cell gene programs define subtype identity and metastatic trajectories in renal cell carcinoma

Ariel Madrigal, Minjun Kim, Zohreh Mehrjoo, Tamiko Nishimura, Özge Saatci, Adrien Osakwe, Evelyn Zavacky, Elham Moslemi, Kate I. Glennon, Matthew Dankner, Sarah M. Maritan, Hellen Kuasne, Virginie Pilon, Anie Monast, Mustafa Soytaş, , Hamed Shateri Najafabadi

This study identifies 59 gene expression programs in RCC that reveal subtype identity and metastatic trajectories, including a metastatic signature linked to poor clinical outcomes.

medRxiv · Jul 16, 2026 · PreprintGenetic & Genomic Medicine

Semantic fragment representations for coordinate-free analysis of genomics data

Hamed Heydari, Jing Zhao, Madeleine Arseneault, Leila Younesian, Simon Tanguay, Yasser Riazalhosseini, Hani Goodarzi, Hamed Shateri Najafabadi

The paper introduces LEAF-1, a fragment-level foundation model for genomics data analysis, showing it can classify cell types and detect cancer from sparse datasets and cell-free DNA.

bioRxiv · Jul 10, 2026 · PreprintGenomics