Author

Mustafa Soytaş

Istanbul Medipol UniversityORCID 0000-0002-3474-3510Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ariel MadrigaliD· 2 shared Fadi BrimoiD· 2 shared Hamed Shateri NajafabadiiD· 2 shared Minjun KimiD· 2 shared Morag ParkiD· 2 shared Özge SaatciiD· 2 shared Ozgur Sahin· 2 shared Simon TanguayiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Ariel MadrigalORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Lysyl oxidase drives ccRCC progression by coordinating HIF-2α transcription program with tumor microenvironment

Bürge Ulukan, Özge Saatci, Ariel Madrigal, Minjun Kim, Wensheng Tian, Mustafa Soytaş, Zohreh Mehrjoo, Ozlem Sener Sahin, Kukkamadi Sreenivas, C.N.R. Rao, Tamiko Nishimura, Virginie Pillon, Jean-Sebastian Anoma, Elizabeth Hill, Janusz Rak, , Ozgur Sahin

This study identifies LOX as a driver of ccRCC progression by sustaining HIF-2α transcription and modulating the tumor microenvironment.

bioRxiv · Jul 27, 2026 · PreprintCancer Biology

Single-cell gene programs define subtype identity and metastatic trajectories in renal cell carcinoma

Ariel Madrigal, Minjun Kim, Zohreh Mehrjoo, Tamiko Nishimura, Özge Saatci, Adrien Osakwe, Evelyn Zavacky, Elham Moslemi, Kate I. Glennon, Matthew Dankner, Sarah M. Maritan, Hellen Kuasne, Virginie Pilon, Anie Monast, Mustafa Soytaş, , Hamed Shateri Najafabadi

This study identifies 59 gene expression programs in RCC that reveal subtype identity and metastatic trajectories, including a metastatic signature linked to poor clinical outcomes.

medRxiv · Jul 16, 2026 · PreprintGenetic & Genomic Medicine