Genome reorganization prior to mitosis shapes the generation of adaptive immunity
Wing Fuk Chan, Hannah D. Coughlan, Jie H. S. Zhou, Christine R. Keenan, Naiara G. Bediaga, Philip D. Hodgkin, Gordon K. Smyth, Timothy M. Johanson, Rhys S. Allan
The paper shows genome reorganization occurs in discrete waves before DNA replication and mitosis, controlling B cell differentiation into plasma cells.
Nature Communications · Feb 26, 2021Peer-reviewedGenomics