Cancer BiologybioRxivPreprint
Gain-of-function mutant p53 regulates long-noncoding RNA LINC00643 to modulate HIF1α in glioblastoma
Ying Zhang, Fang Yuan, Myron Keith Gibert…·Roger Abounader
This study identifies LINC00643 as a target of GOF-MUT-p53 in glioblastoma, showing it suppresses tumor growth by repressing HIF1α under hypoxia.
DOI 10.1101/2025.09.16.676559