Author

Olfat A. Malak

Buck Institute for Research on AgingORCID 0000-0002-9137-6032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aaryan Vira· 1 shared Birgit SchillingiD· 1 shared Christina D. KingiD· 1 shared Chuankai ZhouiD· 1 shared Doyle Lokitiyakul· 1 shared Gabriel Navarro· 1 shared Grant Kauwe· 1 shared Ivy WongiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aaryan Vira

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1 paper

Recent·Most cited

Tau oligomers modulate synapse fate by eliciting progressive bipartite synapse dysregulation and synapse loss

Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe, Yani Y. Ngwala, Doyle Lokitiyakul, Ivy Wong, Aaryan Vira, Yaofu Liu, Jackson H. Chen, Mahima Sharma, Gabriel Navarro, Olfat A. Malak, Chuankai Zhou, Birgit Schilling, Tara E. Tracy

This study shows that tau oligomers cause progressive synapse dysfunction by initially weakening both presynaptic and postsynaptic components, followed by synaptic loss.

Molecular Neurodegeneration · Jan 22, 2026Peer-reviewedNeuroscience