Author

Gregory-Neal W Gomes

Altos LabsORCID 0000-0002-9145-9727Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Zachary A. LevineiD· 3 shared Brittney A. BeyeriD· 1 shared Kamila NurmakovaiD· 1 shared Matthew SteinsaltziD· 1 shared Sang Ho ParkiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 5 mutual co-author links

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3 shared papersBiophysics

Zachary A. LevineORCID

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3 papers

Recent·Most cited

Inhibition of ApoE4 Endocytosis with LDLR-LA Peptides

Sang Ho Park, Gregory-Neal W Gomes, Brittney A. Beyer, Zachary A. Levine

This study designs and evaluates LDLR-LA peptides to inhibit ApoE4 endocytosis, showing isoform-dependent uptake dynamics and identifying LA345 as the most stable construct.

bioRxiv · May 22, 2026 · PreprintBiochemistry

ApoE lipidation, not isoform, is the key modulator of Aβ interaction, uptake, and cytotoxicity

Kamila Nurmakova, Gregory-Neal W Gomes, Zachary A. Levine

This study shows that ApoE lipidation, not isoform, most strongly affects Aβ interaction, uptake, and cytotoxicity in astrocytes.

bioRxiv · Nov 19, 2025 · PreprintBiophysics

Consensus DNA Inhibits p53 Aggregation but Fails to Rescue Mutants

Matthew Steinsaltz, Gregory-Neal W Gomes, Zachary A. Levine

This study investigates whether consensus DNA sequences can regulate p53 aggregation in wild-type and mutant forms, finding that while consensus DNA inhibits wild-type p53 aggregation, oncogenic mutants evade this regulation and may even enhance aggregation.

bioRxiv · Jul 24, 2025 · PreprintBiophysics