Author

Matthew Steinsaltz

Yale UniversityORCID 0000-0003-0241-1666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

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Gregory-Neal W GomesiD· 1 shared Zachary A. LevineiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiophysics

Gregory-Neal W GomesORCID

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1 paper

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BiophysicsbioRxivPreprintJul 24, 2025

Consensus DNA Inhibits p53 Aggregation but Fails to Rescue Mutants

Matthew Steinsaltz, Gregory-Neal W Gomes, Zachary A. Levine

This study investigates whether consensus DNA sequences can regulate p53 aggregation in wild-type and mutant forms, finding that while consensus DNA inhibits wild-type p53 aggregation, oncogenic mutants evade this regulation and may even enhance aggregation.

DOI 10.1101/2025.07.24.665437

humanproteomics

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