Author

Meredith R. McGuire

Johns Hopkins UniversityORCID 0000-0002-9162-4710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Casie S. KubotaiD· 1 shared Chiaki T. IshidaiD· 1 shared Chune LiuiD· 1 shared Debaditya MukhopadhyayiD· 1 shared Hao WangiD· 1 shared Peter John EspenshadeiD· 1 shared Robert A. AndersiD· 1 shared Stephanie L. MyersiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Casie S. KubotaORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedSep 1, 2024

SREBP-dependent regulation of lipid homeostasis is required for progression and growth of pancreatic ductal adenocarcinoma

Chiaki T. Ishida, Stephanie L. Myers, Wei Shao…·Peter John Espenshade

This study shows that SREBP pathway inhibition slows PDAC tumor growth by disrupting lipid homeostasis, suggesting SCAP as a therapeutic target.

19 citations

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