Author

Xiang Fang

Fudan UniversityORCID 0000-0002-9170-0293Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xiang Fang4 papers · National Institute of Metrology

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Huixiao HongiD· 2 shared Jingcheng YangiD· 2 shared Joshua XuiD· 2 shared Lianhua DongiD· 2 shared Luyao ReniD· 2 shared Naixin ZhangiD· 2 shared Wanwan HouiD· 2 shared Weida TongiD· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Huixiao HongORCID

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2 papers

Recent·Most cited

Quartet DNA reference materials and datasets for comprehensively evaluating germline variants calling performance

Luyao Ren, Xiaoke Duan, Lianhua Dong, Rui Zhang, Jingcheng Yang, Yuechen Gao, Rongxue Peng, Wanwan Hou, Yaqing Liu, Jingjing Li, Ying Yu, Naixin Zhang, Jun Shang, Fan Liang, Depeng Wang, , Yuanting Zheng

This paper introduces Quartet DNA reference materials to comprehensively evaluate germline variant calling accuracy across the genome, including difficult regions and batch effects.

Genome biology · Nov 27, 2023Peer-reviewedBioinformatics

Correcting batch effects in large-scale multiomic studies using a reference-material-based ratio method

Ying Yu, Naixin Zhang, Yuanbang Mai, Luyao Ren, Qiaochu Chen, Zehui Cao, Qingwang Chen, Yaqing Liu, Wanwan Hou, Jingcheng Yang, Huixiao Hong, Joshua Xu, Weida Tong, Lianhua Dong, Leming M. Shi, , Yuanting Zheng

The paper evaluates seven batch-effect correction algorithms for multiomic data and finds the ratio-based method is more effective, especially when batch effects are confounded with biological factors.

Genome biology · Sep 6, 2023Peer-reviewedSystems Biology