Qiaochu Chen

Plasma titration provides a physical ruler for cross-platform proteomics

The paper introduces Plasmix, a plasma reference suite, to improve cross-platform proteomics integration by identifying proteins with consistent titration responses across platforms.

A comprehensive personal omics clinical interpreter based on genomic and transcriptomic profiles

The paper introduces POI, a tool that integrates genomic and transcriptomic data to suggest personalized therapies by matching patients to treatments using PreMedKB and predictive algorithms.

The Quartet Data Portal: integration of community-wide resources for multiomics quality control

The Quartet Data Portal provides access to multi-omics reference materials and datasets, along with tools for quality control and community integration.

Multi-omics Quality Assessment in Personalized Medicine through EATRIS

The paper describes EATRIS activities for quality assessment in multi-omics data generation and integration, aiming to support translational medicine through a Multi-Omics Toolbox.

Correcting batch effects in large-scale multiomic studies using a reference-material-based ratio method

The paper evaluates seven batch-effect correction algorithms for multiomic data and finds the ratio-based method is more effective, especially when batch effects are confounded with biological factors.

Quartet metabolite reference materials for assessing inter-laboratory reliability and data integration of metabolomic profiling

The paper establishes reference materials and methods to assess inter-laboratory reliability and data integration in metabolomic profiling.

Ratio-based quantitative multiomics profiling using universal reference materials empowers data integration

This paper introduces ratio-based multiomics profiling using universal reference materials to improve data integration across omics types and batches.