Suspension physics govern the multiscale dynamics of blood flow in sickle cell disease
Hannah M. Szafraniec, Freya Bull, John M. Higgins, Howard A. Stone, Timm Krüger, Philip Pearce, David K. Wood
This study uses a microfluidic platform to link red blood cell properties to whole-blood rheology in sickle cell disease, revealing how stiff cell proportions and spatial organization drive pathological flow resistance.
Science Advances · Jan 1, 2026Peer-reviewedPhysiology