David K. Wood

The paper develops EXACT, a framework combining ex vivo drug screening with transcriptomic analysis to identify effective drug combinations for rare cancers, finding a MEK and HDAC inhibitor combination shows enhanced activity.

This study uses a microfluidic platform to link red blood cell properties to whole-blood rheology in sickle cell disease, revealing how stiff cell proportions and spatial organization drive pathological flow resistance.

This paper develops a 3D collagen-based tumor spheroid model to study macrophage-driven ECM remodeling and its impact on cancer cell invasion and malignancy.

This study uses multiomic analysis to investigate metabolic interactions between colorectal cancer cells and hepatocytes in liver metastasis, revealing metabolic shifts and potential therapeutic targets.