Author

Hannah M. Szafraniec

University of MinnesotaORCID 0000-0002-8525-6990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

David K. WoodiD· 2 shared Freya BulliD· 1 shared Howard A. StoneiD· 1 shared John M. HigginsiD· 1 shared Kathryn L. SchwertfegeriD· 1 shared Luna ZhangiD· 1 shared Paolo P. ProvenzanoiD· 1 shared Philip PearceiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

David K. WoodORCID

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2 papers

Recent·Most cited

PhysiologyScience AdvancesPeer-reviewedJan 1, 2026

Suspension physics govern the multiscale dynamics of blood flow in sickle cell disease

Hannah M. Szafraniec, Freya Bull, John M. Higgins…·David K. Wood

This study uses a microfluidic platform to link red blood cell properties to whole-blood rheology in sickle cell disease, revealing how stiff cell proportions and spatial organization drive pathological flow resistance.

2 citations

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 1, 2025

Collagen-Based Tumor Spheroid Model for Investigating Tumor-Macrophage Interactions through Extracellular Matrix Remodeling

Luna Zhang, Sanab Abdi, Hannah M. Szafraniec…·David K. Wood

This paper develops a 3D collagen-based tumor spheroid model to study macrophage-driven ECM remodeling and its impact on cancer cell invasion and malignancy.

DOI 10.1101/2025.10.01.679587

experimental assaycell-cell communication

𝕏 PostBluesky