Author

Jacopo Gabrielli

Imperial College LondonORCID 0000-0002-9183-6991Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Cleo KontoravdiiD· 2 shared Francesca CeroniiD· 2 shared George ThomiD· 1 shared Justina Briliute· 1 shared Marino Exposito-Rodriguez· 1 shared Matthew R. Burrell· 1 shared Roberto Di BlasiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersSynthetic Biology

Cleo KontoravdiORCID

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Author profile →

2 papers

Recent·Most cited

STAMPS: Signal-peptide Transformer for Augmenting Mammalian Protein Secretion

Jacopo Gabrielli, Marino Exposito-Rodriguez, Justina Briliute, Matthew R. Burrell, George Thom, Cleo Kontoravdi, Francesca Ceroni

STAMPS designs novel mammalian signal peptides to enhance protein secretion, outperforming existing benchmarks in multiple cell lines.

bioRxiv · Nov 20, 2025 · PreprintSynthetic Biology

Degradation Bottlenecks and Resource Competition in Transiently and Stably Engineered Mammalian Cells

Jacopo Gabrielli, Roberto Di Blasi, Cleo Kontoravdi, Francesca Ceroni

This study investigates degradation bottlenecks and resource competition in mammalian cells using degron tags, showing that degradation rates of proteins are coupled due to competition for cellular resources.

Nature Communications · Jan 2, 2025Peer-reviewedSynthetic Biology