Author

David R. Archer

Emory UniversityORCID 0000-0002-9185-0865Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:imaging· 1

Frequent Co-Authors

Hyacinth I. HyacinthiD· 2 shared Andy Y. ShihiD· 1 shared Courtney L Sugihara· 1 shared Jayre A. Jones· 1 shared Noor Abi Rached· 1 shared Raven A. Hardy· 1 shared Thomas Lee SpenceriD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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2 shared papersNeuroscience

Hyacinth I. HyacinthORCID

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2 papers

Recent·Most cited

Age and neuroinflammation are important components of the mechanism of cognitive and neurobehavioral deficits in sickle cell disease.

Raven A. Hardy, Noor Abi Rached, Jayre A. Jones, David R. Archer, Hyacinth I. Hyacinth

This study shows that aging, neuroinflammation, and reduced neuroplasticity contribute to cognitive and neurobehavioral deficits in sickle cell disease, with potential therapeutic benefits from minocycline treatment.

bioRxiv · Mar 24, 2020 · PreprintNeuroscience

Spontaneous development of cerebrovascular pathology and microinfarcts in a mouse model of sickle cell disease.

Hyacinth I. Hyacinth, Courtney L Sugihara, Thomas Lee Spencer, David R. Archer, Andy Y. Shih

This study shows that aged SCD mice develop cerebral vasculopathy features seen in humans, with increased RBC velocity, occlusive events, and microinfarcts detected via in vivo two-photon imaging.

Journal of Cerebral Blood Flow & Metabolism · Sep 19, 2017Peer-reviewedNeuroscience