Author

Mollie S. Schubert

Integrated DNA Technologies (United States)ORCID 0000-0002-9189-2547Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Rolf TurkiD· 2 shared Annalisa LattanziiD· 1 shared Bernice Thommandru· 1 shared Daniel P. DeveriD· 1 shared Garrett R. RettigiD· 1 shared Gavin KurganiD· 1 shared Isabel Ojeda-Pérez· 1 shared Jessica WoodleyiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Rolf TurkORCID

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2 papers

Recent·Most cited

Molecular BiologyScientific ReportsPeer-reviewedSep 30, 2021

✦ In-depth digest

Improved methods and optimized design for CRISPR Cas9 and Cas12a homology-directed repair

Mollie S. Schubert, Bernice Thommandru, Jessica Woodley…·Garrett R. Rettig

Empirical ssODN design rules for Cas9, Cas9 D10A and Cas12a HDR, plus end-modified donors and an NHEJ-inhibiting small molecule, raise HDR up to 10-fold.

123 citationstop 2%

mouseCRISPR screen

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GeneticsMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewedMay 13, 2021

Clinically Relevant Gene Editing in Hematopoietic Stem Cells for the Treatment of Pyruvate Kinase Deficiency Hemolytic Anemia

Sara Fañanas-Baquero, Oscar Quintana Bustamante, Daniel P. Dever…·Jose Carlos Segovia

This study uses gene editing in hematopoietic stem cells to treat Pyruvate Kinase Deficiency Hemolytic Anemia, restoring RPK function and ATP levels in erythroid cells.

22 citations

humanexperimental assay

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