Author

Bernice Thommandru

Integrated DNA Technologies (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Garrett R. RettigiD· 2 shared Gavin KurganiD· 2 shared Matthew McNeilliD· 2 shared Rolf TurkiD· 2 shared Andrea Sánchez PeñaiD· 1 shared Ashley M. JacobiiD· 1 shared Ellen SchmaljohniD· 1 shared He ZhangiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Garrett R. RettigORCID

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2 papers

Recent·Most cited

UNCOVERseq Enables Sensitive and Controlled Gene Editing Off-Target Nomination Across CRISPR-Cas Modalities and Systems

Kyle J. Kinney, Kun Jia, He Zhang, Ellen Schmaljohn, Thomas Osborne, Bernice Thommandru, Karthik Murugan, Andrea Sánchez Peña, Sean C. West, Shengyao Chen, Roshani Codipilly, Morgan L. Sturgeon, Rolf Turk, Matthew McNeill, Mark A. Behlke, , Gavin Kurgan

UNCOVERseq is a workflow for sensitive off-target nomination in CRISPR-Cas editing, demonstrating superior performance across multiple modalities and systems.

Nature Communications · Aug 11, 2026Peer-reviewedMolecular Biology

Improved methods and optimized design for CRISPR Cas9 and Cas12a homology-directed repair

Mollie S. Schubert, Bernice Thommandru, Jessica Woodley, Rolf Turk, Shuqi Yan, Gavin Kurgan, Matthew McNeill, Garrett R. Rettig

Empirical ssODN design rules for Cas9, Cas9 D10A and Cas12a HDR, plus end-modified donors and an NHEJ-inhibiting small molecule, raise HDR up to 10-fold.

Scientific Reports · Sep 30, 2021Peer-reviewedMolecular Biology✦ In-depth digest