Zhuqian Wang

CAR-macrophage immunotherapy targeting fibroblast-like synoviocytes ameliorates inflammatory and degenerative arthritis

This study develops CAR-M2-FAP and CAR-M2-NCL therapies targeting FLS in RA and OA, showing reduced inflammation and joint damage in mouse models.

Targeting nucleolin facilitates the development of blood-tumor barrier-penetrating and glioblastoma-specific PROTACs

This paper develops PROTACs that cross the blood-tumor barrier by targeting nucleolin, showing anti-glioblastoma efficacy without toxicity.