Hequn Zhang

Brain state shapes the polarity of pulsed infrared neural stimulation responses in individual cortical neurons

The paper investigates how brain state affects the polarity of pulsed infrared neural stimulation responses in cortical neurons and develops a method to account for temperature-related fluorescence effects.

Two-photon imaging of excitatory and inhibitory neural response to infrared neural stimulation

The paper uses two-photon calcium imaging to study how infrared neural stimulation affects excitatory and inhibitory neurons in mouse somatosensory cortex.

Precision 1070 nm Ultrafast Laser-induced Photothrombosis (PLP) of Depth-targeted Vessels in vivo

This paper introduces a method for precise, depth-targeted photothrombosis in cerebral vessels using a 1070 nm ultrafast laser and evaluates its effectiveness for studying vascular function.

Solid optical clearing agents based through-Intact-Skull (TIS) window technique for long-term observation of cortical structure and function in mice

This paper develops a TIS window technique for long-term high-resolution cortical imaging in awake mice without skull removal.

Ultra-deep through-skull mouse brain imaging via the combination of skull optical clearing and three-photon microscopy

This paper combines skull optical clearing and three-photon microscopy to achieve deep brain imaging through an intact mouse skull.

Imaging microvasculature network evolution and neurodegeneration with precise photothrombosis approach

This study develops a precise photothrombosis method to investigate microvascular network dynamics and neurodegeneration effects in the cerebral cortex.

AIE-nanoparticle assisted ultra-deep microscopy in the in vivo mouse brain under 1300-nm excitation

This study demonstrates AIE nanoparticles enabling ultra-deep three-photon imaging in live mouse brains using NIR-IIa excitation.