Materials Chemistry FrontiersNeurosciencePeer-reviewed journal article
AIE-nanoparticle assisted ultra-deep microscopy in the in vivo mouse brain under 1300-nm excitation
Dongyu LiiD, Hequn ZhangiD, Lina L. Streich, Yalun Wang, Ping LüiD, Ling WangiD, Robert PrevedeliD, Jun QianiD
Abstract
Aggregation-induced emission nanoparticles serve as promising fluorescence probes for multi-photon excitation microscopy due to the large absorption cross-section at NIR-IIb region. Here we present organic AIE nanoparticles that feature high aborption cross-section under three-photon excitation. We show that these enable ultra-deep NIR-IIa excited three-photon imaging in the in-vivo mouse brain.
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