GenomicsbioRxivPreprint
APOBEC3A, not APOBEC3B, drives deaminase mutagenesis in human gastric epithelium
Yohan An, Ji‐Hyun Lee, Joonoh Lim…·Young Seok Ju
This study shows APOBEC3A, not APOBEC3B, causes significant mutagenesis in human gastric epithelium through whole-genome sequencing of organoids with inducible APOBEC3A or APOBEC3B.
DOI 10.1101/2024.10.28.620744