Author

Ruona Shi

Chinese Academy of SciencesORCID 0000-0002-9202-7280Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Xiaofei ZhangiD· 2 shared Bo WangiD· 1 shared Chengchen ZhaoiD· 1 shared Dan XiangiD· 1 shared Duanqing PeiiD· 1 shared Hanqing Zhao· 1 shared Jiajun LiiD· 1 shared jin ming· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

Xiaofei ZhangORCID

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2 papers

Recent·Most cited

A Phospho-Switch for Cell Fate Control

jin ming, xianzhuang liu, Zexiao Jia, Wei Shi, Jiajun Li, Shikun Wang, yulin chen, Shixian Lin, yu liang, peng guo, Hanqing Zhao, Yuxiang Yao, Ruona Shi, Xiaofei Zhang, Yuanyue Shan, , Duanqing Pei

The paper identifies a phospho-switch in SALL4 that controls cell fate by modulating BAF complex interaction in response to BMP4-DUSP9 signaling, causing developmental defects when disrupted.

bioRxiv · Feb 23, 2026 · PreprintDevelopmental Biology

Unveiling the biochemical catalysis and regulatory mechanisms of the E3-independent E2 enzyme hUBE2O

Dan Xiang, Xiaoxiao Tang, Ruona Shi, Shuqi Dong, Xiaofei Zhang

This study elucidates the catalytic and regulatory mechanisms of hUBE2O, revealing its unique architecture for mono- and polyubiquitination and identifying key residues and zinc ions as regulators.

bioRxiv · Jun 27, 2025 · PreprintBiochemistry