Author

Dan Xiang

Chinese Academy of SciencesORCID 0009-0001-4820-9693Unclaimed ORCID profile · follow to get notified of new preprints

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Dan Xiang2 papers · Northwestern Polytechnical University

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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Ruona ShiiD· 1 shared Shuqi Dong· 1 shared Xiaofei ZhangiD· 1 shared Xiaoxiao TangiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Ruona ShiORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJun 27, 2025

Unveiling the biochemical catalysis and regulatory mechanisms of the E3-independent E2 enzyme hUBE2O

Dan Xiang, Xiaoxiao Tang, Ruona Shi…·Xiaofei Zhang

This study elucidates the catalytic and regulatory mechanisms of hUBE2O, revealing its unique architecture for mono- and polyubiquitination and identifying key residues and zinc ions as regulators.

DOI 10.1101/2025.06.27.661974

humanproteomics

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