Author

Juliet K. Knowles

Stanford UniversityORCID 0000-0002-9214-2991Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew J. SkeltoniD· 1 shared Ankita Batra· 1 shared Caroline Soane· 1 shared Danielle A. Fraga· 1 shared Eleanor FrostiD· 1 shared Haojun XuiD· 1 shared James Staley· 1 shared Jiaqi GuiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Andrew J. SkeltonORCID

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2 papers

Recent·Most cited

Distilling Direct Effects via Conditional Differential Gene Expression Analysis

Jiaqi Gu, Andrew J. Skelton, James Staley, Pierce Oran Popson, Lei Peng, Xiaoyu Song, Juliet K. Knowles, Zihuai He

The paper introduces conditional differential gene expression analysis to distinguish direct from mediated gene effects in RNA sequencing data, finding most differentially expressed genes are not directly causal.

bioRxiv · Sep 29, 2025 · PreprintBioinformatics

Maladaptive myelination promotes epileptogenesis in absence epilepsy

Juliet K. Knowles, Caroline Soane, Eleanor Frost, Lydia T. Tam, Danielle A. Fraga, Haojun Xu, Ankita Batra, Lijun Ni, Katlin Villar, Tristan Saucedo, John R. Huguenard, Michelle Monje

This study shows that maladaptive myelination driven by absence seizures contributes to epileptogenesis in two mouse models of absence epilepsy.

bioRxiv · Aug 20, 2020 · PreprintNeuroscience