Haojun Xu

This study develops iPSC-derived T cells targeting the EGFR C797S mutation in NSCLC, showing their ability to recognize and kill cancer cells expressing this mutation.

This study shows that CAR T cell therapy in mice causes cognitive impairment through CNS immune dysregulation, microglial reactivity, and disrupted oligodendroglial homeostasis.

This study identifies functional GABAergic neuron-to-glioma synapses in diffuse midline gliomas that promote tumor proliferation and shows that drugs modulating GABAergic signaling affect glioma growth.

This study shows that maladaptive myelination driven by absence seizures contributes to epileptogenesis in two mouse models of absence epilepsy.