Christina J. Su

This study investigates the dynamics and functional roles of negative autoregulation by the SF2 splicing factor in single cells, showing its role in regulating protein concentration and reducing cell-to-cell variability.

The paper develops a mathematical model to show how promiscuous ligand-receptor interactions enable efficient cellular addressing through combinatorial signaling.

The paper investigates how BMP ligands interact combinatorially and context-dependently through receptor expression, revealing equivalence groups and a biochemical model for signaling complex formation.