Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages
Gregory J. Fonseca, Jenhan Tao, Emma M. Westin, Sascha H. C. Duttke, Nathanael J. Spann, Tobias Strid, Zeyang Shen, Joshua D. Stender, Mashito Sakai, Verena M. Link, Christopher W. Benner, Christopher K. Glass
The paper identifies non-redundant DNA binding activities of AP-1 family members in macrophages using ChIP-sequencing and machine learning, showing motif ensembles drive factor-specific binding.
Nature Communications · Jan 24, 2019Peer-reviewedGenomics