Author

Si Ning Liu

University of AlbertaORCID 0000-0002-9242-9239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:rat· 2 Research Focus:clustering· 1 Organism:mouse· 1

Frequent Co-Authors

Stephane Louis BourqueiD· 3 shared Anson WongiD· 2 shared Claudia D. HolodyiD· 2 shared Hélène LemieuxiD· 2 shared Ibrahim KhodabocusiD· 2 shared Jad-Julian RachidiD· 2 shared Jennie VuiD· 2 shared Kimberly F. MacalaiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersPhysiology

Stephane Louis BourqueORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Maternal iron deficiency elicits divergent cardiac mitochondrial responses in normotensive and hypertensive pregnancy

Jad-Julian Rachid, Claudia D. Holody, Si Ning Liu, Rohini Roy Roshmi, Navdeep S Badhan, Anson Wong, Alyssa Wiedemeyer, Jennie Vu, Ibrahim Khodabocus, Hélène Lemieux, Stephane Louis Bourque

This study examines how maternal iron deficiency affects cardiac mitochondrial function in hypertensive and normotensive pregnancies, finding altered mitochondrial structure and respiration with no apoptosis.

bioRxiv · Jul 28, 2026 · PreprintPhysiology

Mitochondrial-targeted therapy with elamipretide preserves cardiac function and prevents late mortality in murine sepsis-induced cardiac dysfunction.

Jennie Vu, Cory S. Wagg, Claudia D. Holody, Anson Wong, Takdeer Baidwan, Maryam Lo, Ibrahim Khodabocus, Si Ning Liu, Kimberly F. Macala, Antoine Dufour, John R. Ussher, Hélène Lemieux, Gary D. Lopaschuk, Stephane L. Bourque

This study shows that elamipretide improves cardiac function and prevents mortality in sepsis-induced cardiac dysfunction in mice by restoring mitochondrial function.

bioRxiv · Jul 9, 2026 · PreprintPhysiology

A neonatal rat sepsis score captures the time course and severity of disease in a clinically relevant rat peritonitis model.

Forough Jahandideh, Si Ning Liu, Kimberly B. Tworek, Ronan M. N. Noble, Jad-Julian Rachid, Aileen MacLellan, Manoj Mathew Lalu, Kimberly F. Macala, Stephane L. Bourque

This paper develops a neonatal rat sepsis model and scoring system to monitor disease severity and time course in a clinically relevant polymicrobial sepsis context.

bioRxiv · May 19, 2026 · PreprintPhysiology