Author

Carmen Santa-Cruz Mateos

University of CambridgeORCID 0000-0002-9243-7159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2

Frequent Co-Authors

Sarah J. BrayiD· 2 shared Charalambos S. RoussosiD· 1 shared F Javier deHaro-ArbonaiD· 1 shared Jonathan TownsoniD· 1 shared Julia Falo SanjuaniD· 1 shared Maria J. Gomez-LamarcaiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Sarah J. BrayORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Direct observation of Notch signalling induced transcription hubs mediating gene-expression responses

Carmen Santa-Cruz Mateos, Charalambos S. Roussos, F Javier deHaro-Arbona, Julia Falo Sanjuan, Sarah J. Bray

The paper shows Notch signaling forms transcription hubs that regulate gene expression by correlating hub dynamics with transcription profiles.

bioRxiv · Jul 4, 2025 · PreprintDevelopmental Biology

OptIC Notch reveals mechanism that regulates receptor interactions with CSL.

Jonathan Townson, Maria J. Gomez-Lamarca, Carmen Santa-Cruz Mateos, Sarah J. Bray

The paper uses an optogenetic approach to control Notch signaling and shows that the {Phi}W{Phi}P motif sequesters CSL in the cytoplasm, preventing target gene activation until NICD is released.

Development · May 12, 2023Peer-reviewedDevelopmental Biology