Author

Alesia A. Tietze

Wallenberg Centre for Molecular and Translational MedicineORCID 0000-0002-9281-548XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:benchmarking· 2 Organism:E. coli· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Jordi C. J. HintzeniD· 2 shared Viktor SteiniD· 2 shared Wadim WeberiD· 2 shared Aishe A. SarshadiD· 1 shared Annika ThorselliD· 1 shared Carolin Gebhardt· 1 shared Chunsheng JiniD· 1 shared Daniel BojariD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMolecular Biology

Jordi C. J. HintzenORCID

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4 papers

Recent·Most cited

Extended nuclear glycosylation regulates RNA processing

Jon Lundstrøm, Michelle Fong, Annika Thorsell, Ekaterina Mirgorodskaya, Johannes Fuchs, Ujala Bashir, Jordi C. J. Hintzen, Chunsheng Jin, F. Ifthiha Mohideen, Vivian Lobo, Evgeniya Y. Shcherbinina, Alesia A. Tietze, Lara K. Mahal, Aishe A. Sarshad, Daniel Bojar

The paper shows that extended O-glycans are present on intranuclear proteins and demonstrate their role in RNA processing through specific examples.

bioRxiv · Mar 25, 2026 · PreprintMolecular Biology

Targeted Sortase A Inhibition by Novel Peptidomimetic Antivirulents against Staphylococcal Infections

Jordi C. J. Hintzen, Shadi Rahimi, Daniel Tietze, Jian Zhang, Priyanka Mehra, Ivan Mijakovic̀, Alesia A. Tietze

This study evaluates the selectivity of the peptidomimetic inhibitor BzLPRDSar against Gram-positive bacteria, showing potent inhibition of biofilm formation in multidrug-resistant Staphylococcus species.

Microbiology Spectrum · Mar 3, 2026Peer-reviewedMicrobiology

Scaling the Functional Nanopore (FuN) Screen: Systematic Evaluation of Self-Assembling Membrane Peptides and Extension with a K+-Responsive Fluorescent Protein Sensor

Klara Eisenhauer, Wadim Weber, Philipp Kemp, Carolin Gebhardt, M. Kaufmann, Noel Tewes, Hanna Zhdanova, Alesia A. Tietze, Oliver Rauh, Viktor Stein

The paper evaluates the FuN screen for analyzing self-assembling membrane peptides and extends it with K+-responsive fluorescent protein sensors, benchmarking against traditional biophysical methods.

ACS Synthetic Biology · Apr 10, 2024Peer-reviewedSynthetic Biology

The Functional Nanopore Screen: A Versatile High-throughput Assay to Study and Engineer Protein Nanopores in Escherichia coli

Wadim Weber, Markus Roeder, Tobias Probanowski, Jie Yang, Helal Abujubara, Heinz Koeppl, Alesia A. Tietze, Viktor Stein

The paper introduces a high-throughput assay called the Functional Nanopore screen to study and engineer protein nanopores in E. coli by measuring Ca2+ influx.

ACS Synthetic Biology · May 23, 2022Peer-reviewedSynthetic Biology