Chunsheng Jin

Degradation of mucin O-glycans by a human gut symbiont requires a complex enzyme repertoire and promotes colonization

This study identifies the enzymatic pathway used by Bacteroides thetaiotaomicron to degrade colonic mucin O-glycans and shows that multiple exo-acting enzymes are critical for gut colonization.

Extended nuclear glycosylation regulates RNA processing

The paper shows that extended O-glycans are present on intranuclear proteins and demonstrate their role in RNA processing through specific examples.

Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactation

This study characterizes the structural and functional dynamics of milk oligosaccharides in Atlantic grey seals throughout lactation, revealing complexity comparable to human milk.

The role of Akkermansia muciniphila sulfatases in colonic mucinutilisation

This study investigates the role of Akkermansia muciniphila sulfatases in colonic mucin utilization, revealing unique adaptations compared to Bacteroides species.

Dual human milk oligosaccharide-fibre utilisation drives gut microbiome selection during weaning

The paper investigates how dual utilization of human milk oligosaccharides and dietary fibers influences gut microbiome selection during weaning.

O-glycosylation contributes to mammalian glycoRNA biogenesis

This study demonstrates that O-glycosylation contributes to sialoglycoRNA biogenesis and shows increased sialylation in ulcerative colitis-derived organoids.

Predicting glycan structure from tandem mass spectrometry via deep learning

The paper introduces CandyCrunch, a deep learning model that predicts glycan structures from tandem mass spectrometry data with high accuracy, enabling high-throughput glycomics.

e-workflow for recording of glycomic mass spectrometric data in compliance with reporting guidelines

The paper describes an e-infrastructure for recording glycomic mass spectrometric data in compliance with MIRAGE reporting guidelines, enabling standardized data submission to a public repository.