Author

Bruna C. Bertol

University Health NetworkORCID 0000-0002-9301-449XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

David G. BrooksiD· 1 shared Diala Abd-RabboiD· 1 shared Heidi J. Elsaesser· 1 shared Melissa Yi Ran Liu· 1 shared René Vielman QuevedoiD· 1 shared S. Liu· 1 shared Sabelo LukheleiD· 1 shared Sara LamorteiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

David G. BrooksORCID

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1 paper

Recent·Most cited

Functional Type I and Type II interferon crosstalk restricts progenitor exhausted CD8 T cells through spatial exclusion and checkpoint enforcement

S. Liu, Heidi J. Elsaesser, René Vielman Quevedo, Diala Abd-Rabbo, Bruna C. Bertol, Wenxi Xu, Melissa Yi Ran Liu, Sabelo Lukhele, Sara Lamorte, Tracy L. McGaha, David G. Brooks

This study identifies a spatially encoded interferon circuit that restricts progenitor exhausted CD8 T cells during chronic infection by enforcing niche sequestration and checkpoint control.

bioRxiv · Mar 3, 2026 · PreprintImmunology