David G. Brooks

This study uses high-dimensional immune profiling to identify CD39 as a correlate of tuberculosis disease severity and shows its potential as a therapeutic target.

This study shows that sequential infections in mice remodel immune landscapes, making them more similar to human immunity and affecting future immune responses.

This study identifies a spatially encoded interferon circuit that restricts progenitor exhausted CD8 T cells during chronic infection by enforcing niche sequestration and checkpoint control.

This study characterizes T cell glycosylation patterns across mouse and human tissues, revealing species-specific differences in glycan profiles and dynamics.