Author

Daniela Guidone

Telethon Institute Of Genetics And MedicineORCID 0000-0002-9301-8095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Alessandro UmbachiD· 1 shared Anna CeresetoiD· 1 shared Carmelo GentileiD· 1 shared Daniele ArosioiD· 1 shared Gianluca PetrisiD· 1 shared Giulia MauleiD· 1 shared Irene CarrozzoiD· 1 shared Luis J. V. GaliettaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Alessandro UmbachORCID

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1 paper

Recent·Most cited

Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editing

Irene Carrozzo, Giulia Maule, Carmelo Gentile, Alessandro Umbach, Matteo Ciciani, Daniela Guidone, Martina De Santis, Gianluca Petris, Luis J. V. Galietta, Daniele Arosio, Anna Cereseto

This study uses CRISPR base editing to introduce revertant mutations in F508del-CFTR, rescuing protein folding and function in CF patient-derived cells.

Molecular Therapy · Jan 9, 2025Peer-reviewedBioengineering