Reduction of Grin2a in adolescent rat dopamine neurons confers a phenotype relevant to psychosis
Michelle L. Kielhold, David S. Jacobs, Alejandro Torrado Pacheco, Merridee J. Lefner, Joseph J. Lebowitz, Angela Langdon, John T. Williams, Larry S. Zweifel, Bita Moghaddam
This study shows that reducing Grin2a in adolescent rat dopamine neurons leads to psychosis-like behaviors and dopamine signaling abnormalities relevant to schizophrenia.
bioRxiv · Oct 28, 2024 · PreprintNeuroscience