Joseph J. Lebowitz

The synaptic vesicle priming protein Munc13 mediates evoked somatodendritic dopamine release

This study investigates the role of Munc13 in evoked somatodendritic dopamine release in dopamine neurons, finding it essential for evoked but not spontaneous release.

Reduction of Grin2a in adolescent rat dopamine neurons confers a phenotype relevant to psychosis

This study shows that reducing Grin2a in adolescent rat dopamine neurons leads to psychosis-like behaviors and dopamine signaling abnormalities relevant to schizophrenia.

Dopamine D2 receptors in mossy cells reduce excitatory transmission and are essential for hippocampal function

This study shows that dopamine D2 receptors in mossy cells reduce excitatory transmission and are essential for hippocampal function, with implications for anxiety and epilepsy.

Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in a Mouse Model of the Human Pathogenic Mutation DRD2I212F

This paper describes a mouse model with the DRD2I212F mutation, showing gait abnormalities and altered dopamine receptor signaling.

Synaptotagmin-7 enhances phasic dopamine release

This study shows that synaptotagmin-7 enhances phasic dopamine release in SNc neurons by mediating short-term facilitation during high-frequency firing.