John T. Williams

This study investigates the role of Munc13 in evoked somatodendritic dopamine release in dopamine neurons, finding it essential for evoked but not spontaneous release.

This study shows that reducing Grin2a in adolescent rat dopamine neurons leads to psychosis-like behaviors and dopamine signaling abnormalities relevant to schizophrenia.

The paper develops improved GRABDA sensors to monitor dopaminergic activity in vivo, showing high sensitivity and spatially resolved DA release in mice during behaviors.

This paper describes a mouse model with the DRD2I212F mutation, showing gait abnormalities and altered dopamine receptor signaling.

This study shows that synaptotagmin-7 enhances phasic dopamine release in SNc neurons by mediating short-term facilitation during high-frequency firing.

This study shows that phosphorylation of the μ-opioid receptor (MOR) is essential for desensitization, internalization, and long-term tolerance to morphine in locus coeruleus neurons.